In the Know: New reports, resources, guidelines

• American Academy of Orthopedic Surgeons clinical practice guidelines on the treatment of carpal tunnel syndrome
• American College of Physicians pharmacologic treatment of low bone density or osteoporosis to prevent fractures: A clinical practice guideline
• FDA advisory February 4, 2009: Xigris (Dotrecogin alfa [activated]): The FDA is working with the manufacturer to further evaluate the incidence of serious bleeding events and mortality. FDA will communicate its conclusions and any resulting recommendations to the public when the review is complete.